Sleep Less, Eat More, Gain Weight

By Carrie Gann

Obesity linked to hormonal changes, lack of sleep

We’ve all heard about the importance of getting a good night’s sleep, and now scientists offer more evidence to back that up. A new study found that people who get less sleep may be inclined to eat more, move less and gain weight.

Scientists at the Mayo Clinic in Rochester, Minn., studied a group of 17 healthy volunteers between the ages 18 and 40 for a week in their homes, monitoring how much each one typically slept and ate. Then, they brought the volunteers into the clinic’s research lab for eight days: Half of the volunteers were allowed to sleep according to their usual pattern, and the other half got only two-thirds of their usual shut-eye.

All the volunteers were allowed to eat as much food as they wanted from the hospital cafeteria or from outside the research center. The researchers also measured how much energy each volunteer expended each day.

The sleep-deprived participants wolfed down an average of 549 calories beyond their usual intake but burned no more calories than their well-rested peers.

“A lot of people have this idea that if they’re up late, working hard, they’re burning more energy. But we found no change in how much they moved when sleep deprived,” said Dr. Andrew Calvin, lead author of the study and an assistant professor of medicine at the Mayo Clinic. “They’re consuming an additional 549 calories per day, but not burning any of them off.”

Those excess of unburned calories is a surefire way to gain weight, which numerous studies have connected to a variety of chronic health problems.

The volunteers who got less sleep also had higher levels of leptin, a hormone that suppresses appetite, and lower levels of ghrelin, a hormone that stimulates appetite, in their blood. The findings seem counterintuitive to what researchers would expect in people who are hungrier, but Calvin said the hormones were most likely an outcome, rather than a cause of people eating more.

Scientists have previously studied the physical downsides of getting too little sleep.

In 2011, Australian researchers found that adolescents and teenagers were more likely to be slimmer if they went to bed earlier, while those who stayed up late were more likely to engage in sedentary activities.

Previous studies have also found that workers covering late and overnight shifts were more likely to be obese and have type 2 diabetes, which may be associated with unhealthy eating habits, according to an editorial published in December.

The connection between sleep and weight may be important for the more than one-quarter of Americans who get six hours of sleep or less every night. Calvin said the future research on how sleep affects eating habits may give scientists useful insights into two of America’s biggest health problems: sleep deprivation and obesity.

“This study, while small, suggests that these two may indeed be linked, and if the findings are confirmed, they may suggest that sleep is a powerful factor in how much we eat and our chances of gaining weight,” he said.

Source: http://abcnews.go.com/blogs/health/2012/03/14/sleep-less-eat-more-gain-weight/

Enhanced by Zemanta

Overeating May Double Risk of Memory Loss

By Steven Reinberg – HealthDay Reporter

Too many calories could lead to early signs of Alzheimer’s, preliminary research suggests.

Overeating May Double Risk of Memory LossOlder people who eat too much are at risk for memory impairment, a new study contends.

People 70 and older who eat between 2,100 and 6,000 calories a day may be at double the risk of these deficits in memory, which can be an early sign of Alzheimer’s disease, the study authors said.

“Excessive daily caloric consumption may not be brain-health friendly,” said lead researcher Dr. Yonas Geda, an associate professor of neurology and psychiatry at the Mayo Clinic in Scottsdale, Ariz.

“It may sound like a cliche, but we need to be mindful of our daily caloric consumption,” he said. “The bottom line is that eating in moderation, not in excess amount, may be good for your brain.”

The results of the study are due to be presented in April at the annual meeting of the American Academy of Neurology, in New Orleans. The data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

For the study, investigators collected data on more than 1,200 people, aged 70 to 89, living in Olmsted County, Minn. Among these people, 163 had been diagnosed with the memory deficits known as “mild cognitive impairment.”

Each person told the researchers how much they ate. One-third ate between 600 and 1,525 calories a day, one-third between 1,526 and 2,142 calories a day, and one-third ate between 2,143 and 6,000 calories a day.

Among those who ate the most, the odds of being diagnosed with the impaired-memory disorder was more than twice that of those who ate the least, the researchers found.

There was no significant increase in risk for memory problems among those in the middle group, the researchers added.

These findings remained the same after taking into account a history of stroke, diabetes, education and other risk factors for memory loss.

“We also looked at BMI and obesity,” Geda said. BMI, or body mass index, is a measurement based on height and weight. “But there was no significant difference between the normal [participants] and mild cognitive impairment when it comes to these two variables,” he said.

Why overeating affects the brain isn’t clear, but “excessive caloric intake may lead to oxidative damage leading to structural changes in the brain,” Geda suggested.

Commenting on the study, Dr. Neelum Aggarwal, an associate professor of neurological sciences at Rush University in Chicago, said that “as the population of the U.S. is aging at a rapid rate, in addition to becoming increasingly obese, physicians are being asked by their elderly patients about their risk for various diseases, specifically cognitive [mental] decline and dementia.”

These findings allow doctors to start the discussion about the links between common healthy living practices — eating a nutritious diet, limiting sugar — to overall brain function, he said.

“This study furthers the discussion of what the possible mechanisms are for the development of cognitive decline and offers strategies for disease prevention through nutrition and caloric restriction,” Aggarwal said.

Another expert, David Loewenstein, a professor of psychiatry and behavioral sciences at the University of Miami Miller School of Medicine, said that “this makes a lot of sense because increased caloric intake is associated with obesity and metabolic syndrome, so it is not at all surprising that increased calories are associated with increased cognitive impairment.” Metabolic syndrome is a group of risk factors linked to heart disease and other health problems.

“This study suggests that anything that’s good for the heart — like decreased calories — is good for the brain,” Loewenstein added.

While the study found an association between overeating and memory impairment, it did not prove a cause-and-effect relationship.

Source: http://consumer.healthday.com/Article.asp?AID=661692

Enhanced by Zemanta